Protein Details: Potassium voltage-gated channel subfamily C member 1

Function

Voltage-gated potassium channel that plays an important role in the rapid repolarization of fast-firing brain neurons. The channel opens in response to the voltage difference across the membrane;forming a potassium-selective channel through which potassium ions pass in accordance with their electrochemical gradient. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNC2;and possibly other family members as well. Contributes to fire sustained trains of very brief action potentials at high frequency in pallidal neurons

Sequence

PDB Structures

Ligand Binding